2026-05-05T18:55:19Zhttps://www.radar-service.eu/oai/OAIHandler

10.22000/2802023-11-15T14:42:35Z

10.22000/280 Wittenburg, Dörte Dörte Wittenburg 0000-0002-3639-2574 Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany 2019 2020 Agriculture Biology Life Science Genetics SNP, recombination rate, linkage disequilibrium genotypic data Open Access Creative Commons Attribution 4.0 International Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany In Hampel et al. (2018, Fron Genet), we proposed an advanced method for the estimation of paternal recombination rate and maternal linkage disequilibrium between pairs of SNPs if genotypes of paternal half sibs were available. To show practical usability of the approach, empirical bovine data comprising several half-sib families have been investigated. However, the outcome of our method strongly depended on the order of SNPs. For instance, candidates of putatively misplaced SNPs were identified if recombination rate between close SNPs was unusually high. Since the bovine genome assembly has been updated to its current version ARS-UCD1.2, it was necessary to re-analyse the data. The parameter estimates as well as the input data are now jointly available from this repository. More details about the methodology can be found in Hampel et al. (2018, Fron Genet), https://doi.org/10.3389/fgene.2018.00186. 10.3389/fgene.2018.00186 Federal Ministry of Education and Research (BMBF) 0315137 application/x-tar