2026-05-27T22:54:28Zhttps://www.radar-service.eu/oai/OAIHandler10.35097/qec954fvka86gcjw2025-01-20T18:54:34Zradar4kit
10.35097/qec954fvka86gcjw
Linder, Moritz
Moritz
Linder
0009-0000-1228-159X
Karlsruhe Institute of Technology (KIT)
Loewe, Axel
Axel
Loewe
0000-0002-2487-4744
Karlsruhe Institute of Technology
Sympathetic Stimulation Can Compensate for Hypocalcaemia-Induced Bradycardia in Human and Rabbit Sinoatrial Node Cells (v1.0)
openCARP
2025
2025
Biology
cardiac electrophysiology
openCARP experiment
in-silico medicine
computational cardiology
sinoatrial node cell models
autonomic regulation
cAMP-PKA signalling
coupled clock system
Computer simulation
biomedical engineering
cardiology
LifeScience
ComputerScience
Medicine
Open Access
Apache License 2.0
Karlsruhe Institute of Technology (KIT)
https://ror.org/04t3en479
This experiment simulates the extended sinoatrial node cell models of Severi et al. (2012) and Fabbri et al. (2017) with several [Ca2+]o and [ISO]. The extension of the AC-cAMP-PKA signalling cascade is based on the work of Behar et al. (2016).
en
European Commission
https://ror.org/00k4n6c32
101172576
European High-Performance Computing Joint Undertaking EuroHPC (JU) - MICROCARD-2
application/x-tar